KCTU | Service Index

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Data Sharing Requests 
ArchivedRandomisationACESATHOMEISRCTN58902324PendingN/A
Alternative CErvical Screening – At Home The overall aim is to provide evidence for urine-based cervical screening in current non-attenders of cervical screening, including preference of screening methods and the feasibility of at-home testing for the future.
ArchivedRandomisationACLIMAGENCT04958655PendingN/A
Estimating the acute impact of competing mental imagery on craving in alcohol use disorder.
ArchivedRandomisationACTfRISRCTN68540929PublishedN/A
ACT for Recovery
ArchivedRandomisationACTIBISRCTN44427879PublishedDownload
Assessing Cognitive behavioural Therapy in Irritable Bowel
ArchivedRandomisationACTMUSNCT02810028PublishedN/A
Acceptance and Commitment Therapy for Muscle Disease
ArchivedRandomisationADAPTISRCTN15090567PublishedN/A
The role of anti-IgE (omalizumab) in the management of severe recalcitrant paediatric atopic eczema
LiveRandomisationADAPT_ExISRCTN13944706PendingN/A
The ADAPT trial: A randomised controlled trial to investigate the effectiveness of online exercise interventions in reducing fatigue and the high burden of mental health symptoms in rheumatology patients
ArchivedRandomisationADEPTISRCTN81203286PublishedN/A
Optimising psychological treatment for Anxiety DisordErs in Pregnancy: a feasibility treatment trial
ArchivedRandomisationADeSSNCT03628027PublishedN/A
The Antidepressant Advisor: A decision support system for UK primary care – a feasibility study
ArchivedRandomisationADVANCEISRCTN79435190PublishedN/A
Feasibility and acceptability of a randomised controlled trial of an integrated group intervention to reduce intimate partner violence perpetration among men receiving treatment for substance use
CompletedEDCADVANCEISRCTN66619273PublishedN/A
Feasibility of adapting and delivering the ADVANCE technology-enabled intervention to reduce intimate partner abuse by men receiving substance use treatment
Archived-ClosedRandomisationADVANCE_FullISRCTN66619273PendingN/A
A randomised controlled trial of the ADVANCE integrated group intervention to reduce intimate partner abuse perpetration by men receiving treatment for substance use
LiveEDCADVANCE-DISRCTN95692133PendingN/A
A UK multi-centre cluster randomised control trial, with internal pilot, of the ADVANCE-Digitally supported perpetrator intervention compared to community justice offender management (1:1), to reduce intimate partner violence (IPV), for men convicted of IPV who misuse substances (ADVANCE-D trial)
ArchivedRandomisationAerosureCFNCT01923753PendingN/A
A short – term comparative study of Aerosure for airway clearance in patients with cystic fibrosis
ArchivedRandomisationAerosureCOPDNCT02007590PendingN/A
Does high-frequency airflow oscillation, delivered using Aerosure, increase exercise capacity in severe chronic obstructive pulmonary disease?
LiveEDCALTOISRCTN12680338PendingN/A
Arthritis prevention in the pre-clinical phase of rheumatoid arthritis with abatacept long-term outcome study
AbandonedRandomisationAMBICN/AAbandonedN/A
A randomised controlled trial of community brief mentalization based therapy compared to psychiatric admission in borderline personality disorder : a study of clinical outcome and cost difference
ArchivedRandomisationAMBITIONISRCTN37625384PublishedN/A
Mindfulness-based crisis interventions (MBCI) for psychosis within acute inpatient psychiatric settings: a feasibility randomised controlled trial
ArchivedRandomisationAneurysmCareISRCTN65746249PublishedN/A
Aneurysm Care Pilot Study
ArchivedRandomisationAPIPPRA_NETHERLANDSISRCTN46017566PublishedN/A
Arthritis Prevention In the Pre-clinical Phase of RA with Abatacept (APIPPRA)
ArchivedRandomisationAPIPPRA_UKISRCTN46017566PublishedN/A
Arthritis Prevention In the Pre-clinical Phase of RA with Abatacept (APIPPRA)
ArchivedRandomisationAPRICOT2015-003600-23PublishedN/A
Treatment of pustular psoriasis with the IL-1 receptor antagonist anakinra: a randomised, placebo controlled trial and associated mechanistic studies
ArchivedRandomisationAPRILNCT05865249PendingN/A
Artificial intelligence in PRImary Care spirometry pathways for diagnosis of Lung Disease (APRIL)
ArchivedRandomisationARCISRCTN69313751PublishedN/A
The Addiction Recovery Clinic (ARC): personalised behavioural intervention for opioid use disorder
ArchivedRandomisationARIAISRCTN13832085PendingN/A
A randomised controlled trial to assess the clinical-, technical- and cost-effectiveness of a cloud-based, ARtificially Intelligent image fusion system in comparison to standard treatment to guide endovascular Aortic aneurysm repair
ArchivedRandomisationASCOTISRCTN30012492PublishedN/A
A phase 3 multi-center double masked randomised controlled trial of adjunctive intraocular and periocular steroid (triamcinolone acetonide) versus standard treatment in eyes undergoing viteroretinal surgery for open globe trauma
ArchivedRandomisationASPIISRCTN57199411PublishedN/A
Anxiety Symptoms Prevention Investigation (ASPI): Transmission of anxiety from parent to child ? investigating cognitive-behavioural processes, developing and piloting a brief preventative intervention
ArchivedRandomisationATLANTISISRCTN77257074PendingN/A
AnTiconvuLsant AugmeNtation Trial In Schizophrenia: a randomised, pragmatic double-blind, placebo-controlled trial to assess the effectiveness of valproate augmentation of antipsychotic treatment in patients with residual psychotic symptoms
ArchivedRandomisationATOMISRCTN25691213AbandonedN/A
Atomoxetine for attention deficit hyperactivity disorder (ADHD) in children with special educational needs
LiveRandomisationATTENDISRCTN17687131PendingN/A
ATTEND: Adolescents and carers using mindfulness Therapy To END depression
ArchivedRandomisationATTENSISRCTN82129325PendingN/A
A multi-centre, blinded, randomized, parallel-group, phase IIb study to compare the efficacy of real versus sham Trigeminal Nerve Stimulation (TNS) on symptoms in youth with Attention-Deficit/Hyperactivity Disorder
ArchivedRandomisationAVATARISRCTN65314790PublishedN/A
Reducing the frequency and severity of auditory hallucinations: a randomised clinical trial of a novel Audio-Visual Assisted Therapy Aid for Refractory auditory hallucinations (AVATAR) compared to supportive counselling
ArchivedRandomisationAVATAR2ISRCTN55682735PublishedDownload
Optimising AVATAR therapy for distressing voices: a multi-centre randomised controlled trial
ArchivedRandomisationAwareISRCTN17631228PendingN/A
Promoting mental health and wellbeing in schools: examining Youth Aware of Mental Health (YAM) and the Mental Health & High School Curriculum Guide (The Guide) in English secondary schools
LiveRandomisationBalanceACTNCT06231238PendingN/A
A randomised controlled trial assessing the efficacy of balance acceptance and commitment therapy (ACT) for Long COVID
ArchivedRandomisationBalancingACTISRCTN73327972PendingN/A
Balancing ACT: Evaluating the effectiveness of psychoeducation and Acceptance and Commitment Therapy (ACT) groups for people with bipolar disorder.
ArchivedRandomisationBapEFLISRCTN10950727PendingN/A
Feasibility Randomised Controlled Trial of Being a Parent- Enjoying Family Life: a specialised intervention for parents with significant emotional and interpersonal needs.
ArchivedRandomisationBARILIFESTYLENCT03214471PublishedN/A
Evaluation of the effect of a post-surgery lifestyle intervention compared to usual care upon post-surgery weight loss and changes in body composition, physical activity levels and health-related quality of life in the first year following bariatric surgery
TestingRandomisationBDEPISRCTN81388388pendingN/A
Home-based transcranial direct current stimulation in bipolar depression: a randomised, double-blind, placebo-controlled trial
LiveRandomisationBEACONISRCTN11056540PendingN/A
Best Systemic Treatments for Adults with Atopic Eczema over the Long Term
ArchivedRandomisationBeMindISRCTN52684820PublishedN/A
A comparison to two types of group behaviour therapy for obsessive compulsive disorder: A pilot randomised controlled trial of behaviour therapy and mindfulness-based behaviour therapy for OCD
LiveEDCBESSTISRCTN90912799PublishedN/A
Brief Educational workshops in Secondary Schools Trial: a multi-centre cluster randomised controlled trial of self-referral psychological stress workshops in schools for depression and anxiety in 16-18 year-olds.
ArchivedRandomisationBIORAPAIN2019-004468-23PublishedN/A
Comparison of abatacept with tumor necrosis factor inhibitors in the treatment of rheumatoid arthritis pain: A phase IV trial
ArchivedRandomisationBISCORTISRCTN70836126PendingN/A
Does a breathlessness intervention service (‘CBIS’) reduce stress significantly more than usual care in breathless patients with advanced non-malignant disease and their carers? A phase II feasibility study
MigratedRandomisationBOPPPISRCTN10324656PendingN/A
Beta-blockers or placebo for primary prophylaxis of oesophageal varices. A blinded, multi-centre, clinical effectiveness and cost-effectiveness randomised controlled trial.
LiveRandomisationBOPPPISRCTN10324656PendingN/A
Beta-blockers or placebo for primary prophylaxis of oesophageal varices. A blinded, multi-centre, clinical effectiveness and cost-effectiveness randomised controlled trial.
ArchivedRandomisationBreathePlusISRCTN13051922PublishedN/A
Breathe Plus: Feasibility trial of a comprehensive geriatric assessment for people with COPD and frailty attending pulmonary rehabilitation
ArchivedRandomisationBREATHLESSNESSNCT01165034PublishedN/A
Development of King’s College Hospital Breathlessness Service
ArchivedRandomisationBReFISRCTN91238019PublishedN/A
Cognitive Behavioural Therapy (CBT) for Renal Fatigue (BReF): A feasibility pilot randomised-controlled trial of CBT for the management of fatigue in haemodialysis (HD) patients.
ArchivedRandomisationCAcTUSNCT03808441PendingN/A
A parallel arm, biomarker driven, phase II feasibility trial to determine the role of circulating tumour DNA in guiding a switch between targeted therapy and immune therapy in patients with advanced cutaneous melanoma
ArchivedRandomisationCADMUSNCT02712684PendingN/A
Multi-parametric Ultrasound targeted biopsies compared to Multiparametric MRI targeted biopsies in the diagnosis of clinically significant prostate cancer
ArchivedRandomisationCaFIISRCTN12622538 PendingN/A
The effect on relapse of Culturally-adapted Family Intervention (CaFI) compared to usual care among Sub-Saharan African & Caribbean people diagnosed with psychosis in the UK: A Randomised Controlled Trial
ArchivedRandomisationCALLMEISRCTN71271888PendingN/A
Care Augmentation by Location-Linked Messaging
Archived-ClosedRandomisationCANPDP2019-003623-37PendingN/A
Cannabidiol for Parkinson’s Disease Psychosis
ArchivedRandomisationCANWALKISRCTN42072606PublishedN/A
A study to assess the acceptability and feasibility of a walking intervention for people with recurrent or metastatic cancer
ArchivedRandomisationCAREERISRCTN17767032PublishedN/A
CAReer management to improve Education, Employment and Retention for people with anxiety and depression
ArchivedRandomisationCASAAFISRCTN18250790PublishedN/A
Catheter Ablation vs. Thoracoscopic Surgical Ablation in Long-Standing Persistent Atrial Fibrillation
ArchivedRandomisationCASISISRCTN06149665PublishedN/A
A randomised pragmatic trial comparing the cost effectiveness of supplementing standard care with an intervention for carers (Carers Assessment, Skills and Information Sharing [CASIS]) of people with eating disorders
ArchivedRandomisationCBDVR2ISRCTN11082858PendingN/A
The effect of CBD on paranoid cognitions in humans
ArchivedRandomisationCBMpaISRCTN90749868PublishedN/A
Cognitive Bias Modification for Paranoia
DevelopmentRandomisationCCP_RCTpendingpendingN/A
pending
ArchivedRandomisationCIAOIIISRCTN16827947PublishedDownload
Randomised controlled trial of the short term effects of OROS-methylphenidate on ADHD symptoms and behavioural outcomes in young male prisoners with attention deficit hyperactivity disorder
ArchivedRandomisationCICADAISRCTN48328178AbandonedDownload
Inhibiting white blood cell function as a new way to treat coronary heart disease
ArchivedRandomisationCIICNCT03656653 PublishedN/A
Clinical Study of Imagery-based Coping for Cocaine Use Disorder
CompletedCollaborationCindy Cooper (CI)N/ACompletedN/A
Learning from COVID-19 related trial adaptations to inform efficient trial design-a sequential mixed methods study
LiveRandomisationCIRCuiTSMSNCT06877273pendingN/A
CIRCuiTS MS: Improving cognitive recovery in multiple sclerosis
ArchivedRandomisationCLARITYISRCTN32207582PublishedDownload
Clinical Efficacy and Mechanistic Evaluation of Aflibercept for Proliferative Diabetic Retinopathy (CLARITY). A Multicentre Phase IIb Randomised Active-Controlled Clinical trial.
ArchivedRandomisationCLASSICISRCTN26634837PublishedDownload
Can ‘self-confidence workshops’ for depression help the implementation of the NICE Guidelines?
LiveRandomisationCLEARISRCTN37176025PendingN/A
CLOZAPINE IN EARLY PSYCHOSIS (CLEAR): A MULTI-CENTRE, RANDOMISED CONTROLLED TRIAL OF CLOZAPINE FOR YOUNG PEOPLE WITH TREATMENT RESISTANT PSYCHOSIS IN REAL WORLD SETTINGS
LiveEDCCLEMPTSISRCTN10416636PendingN/A
Closed-Loop Electronic stimulation - Mechanomyogram sensor system for Passive tremor Suppression treatment (CLEMPTS)
ArchivedRandomisationCLEOPATRAISRCTN85596558PublishedDownload
The clinical efficacy and safety of light-masks at preventing dark adaptation in the treatment of early diabetic macular oedema: A Multicentre Phase III Randomised Controlled Single-Masked Clinical trial
ArchivedRandomisationCLIPISRCTN18067579PublishedDownload
Pharmacokinetic study of a novel lipid formulation of cannabidiol (CBD)
ArchivedTherapy RatingCODESISRCTN05681227PublishedN/A
COgnitive behavioural therapy vs standardised medical care for adults with Dissociative non-Epileptic Seizures: A multicentre randomised controlled trial
ArchivedRandomisationCODESISRCTN05681227PublishedN/A
COgnitive behavioural therapy vs standardised medical care for adults with Dissociative non-Epileptic Seizures: A multicentre randomised controlled trial
ArchivedRandomisationCommonGroundNCT06222346PendingN/A
Online peer support in long-term conditions: A feasibility randomised controlled trial.
ArchivedRandomisationCOMPASSISRCTN21454676PendingN/A
Communication-centred Parent-mediated treatment for Autism Spectrum Disorder in South Asia
ArchivedTherapy RatingCONMANISRCTN72794493PublishedN/A
Contingency management targeting increased completion of hepatitis B (Hep B) vaccination amongst people in treatment for heroin dependence
ArchivedRandomisationCONMANISRCTN72794493PublishedN/A
Contingency management targeting increased completion of hepatitis B (Hep B) vaccination amongst people in treatment for heroin dependence
ArchivedRandomisationCONVINCENCT02543021PublishedDownload
A study to assess the feasibility and patient acceptability of a randomised, crossover design to compare virtual vs conventional chromoendoscopy for the detection of dysplasia in colitis
ArchivedRandomisationCOPeISRCTN89563420PublishedN/A
EFFIP (E-support for Families and Friends of Individuals affected by Psychosis): A randomised controlled trial of a co-produced online intervention for carers
CompletedEDCCOPE_HewittN/APublishedDownload
The effect of frailty on survival in patients with COVID-19 (COPE): a multicentre, European, observational cohort study
ArchivedRandomisationCORALNCT01379014PublishedN/A
COnceal or ReveAL
ArchivedRandomisationCRAVINGISRCTN16462783PublishedN/A
Pilot Feasibility Study of Cognitive Control in Cocaine Dependence
ArchivedRandomisationCRiBISRCTN32290525PublishedN/A
Cognitive Remediation in Bipolar disorder: a feasibility study
LiveRandomisationCRIB2ISRCTN10362331PendingN/A
Cognitive Remediation in Bipolar (CRiB2): a randomised trial assessing efficacy and mechanisms of cognitive remediation therapy compared with usual care
ArchivedRandomisationCRIMSONISRCTN11501328PublishedN/A
CRIMSON Study: Randomised controlled trial (RCT) of Joint Crisis Plans to reduce compulsory treatment of people with psychosis
ArchivedRandomisationCRISPISRCTN98067793PublishedDownload
Critical time intervention for severely mentally ill released prisoners
ArchivedRandomisationCRUNCHISRCTN33260236PublishedN/A
Development of a randomized controlled trial to increase cereal fibre intake to reduce insulin resistance in children.
ArchivedRandomisationCTARSWIFTISRCTN12813363PendingN/A
Chin Tuck Against Resistance with Feedback: Swallowing Rehabilitation in Frail Older People - A feasibility study
ArchivedRandomisationCUESISRCTN13766770PublishedN/A
Coping with Unusual Experiences in Children Study
LiveCollaborationCues-EDISRCTN11445338PendingN/A
A cluster randomised, 16-week, parallel-group multicentre trial to compare the effectiveness of a digital school-based cognitive behavioural resilience/wellbeing-building intervention (CUES for schools) targeting emotional and behavioural problems in vulnerable year 4 primary school children in whole classes, compared to the usual school curriculum.
ArchivedRandomisationCUESPLUSISRCTN21802136PendingN/A
Coping with Unusual ExperienceS for 12-18 (CUES+)
ArchivedRandomisationDAISIESISRCTN10166784PublishedN/A
A Randomised Controlled Multi-Centre Open-Label Parallel Group Non-Inferiority Trial of the Clinical Effectiveness, Acceptability and Cost-Effectiveness of a ‘Stepping into Day Treatment’ Approach versus Inpatient Treatment as Usual for Anorexia Nervosa in Adult Specialist Eating Disorder Services (DAISIES Trial)
ArchivedRandomisationDATESISRCTN10342151PendingN/A
Diabetes And Telecommunications Study to support self-management for people with type 2 diabetes: a randomized controlled trial(The DATES trial)
ArchivedRandomisationDAWNISRCTN83768230PublishedN/A
Depression: a trial of antenatal guided self help for women
LiveCollaborationDEEPN/APendingN/A
Emerging evidence on the impact of COVID-19 on mental health services and health inequalities in highly deprived communities.
ArchivedRandomisationDFEND2014-002639-32PublishedN/A
A randomised, double-blind, placebo-controlled, parallel-group trial of Vitamin D supplementation compared to placebo in people presenting with their First Episode of psychosis Neuroprotection Design (DFEND)
ArchivedRandomisationDiabetesStopWatchNCT02919397PublishedN/A
Motivational Instant Messaging and E-diabetes Prevention Programme for High Risk of Type 2 Diabetes
ArchivedRandomisationDIMESISRCTN13339678PublishedN/A
Insulin intervention development for people with type 2 diabetes
ArchivedRandomisationDISCOVERISRCTN88636606PublishedN/A
Early intervention for depression and anxiety in 16-18 year olds: a feasibility trial of open-access psychological workshops in schools
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*Data Sharing Requests: Click the 'Download' link in the Data Sharing Requests column for information on data collected during the study.
(Note, only available for Published Studies where permission has been granted by the Chief Investigator).